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Some individuals report that their hunger signals remain low enough to skip meals without discomfort, while others describe food simply becoming less interesting or rewarding

The Danish pharma group lost no time in slamming Hims & Hers' move, saying it deplores the plan to "unlawfully mass-market an unapproved, inauthentic, and untested knockoff semaglutide pill." In a statement, it said: "The action by Hims & Hers is illegal mass compounding that poses a significant risk to patient safety

Generic competition will reduce medication prices significantly

While tirzepatide is generally well-tolerated, certain side effects warrant prompt medical attention

Individual patients can serve on FDA advisory committees and provide advice to FDA through the Patient Representative Program (FDA, 2024a), while at EMA patients and organizations can apply to be part of a database of patients who can be called on by EMA during the drug evaluation process (EMA, 2022a)

GLP-1-based therapies, such as GLP-1 receptor agonists, glucose-dependent insulinotropic polypeptide (GIP) receptor agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors, improve glucose control through various mechanisms including increased insulin secretion, slower gastric emptying, and reduced postprandial glucagon and food intake