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Our results indicate that exendin-4 increased CSMC cAMP levels in a dose-dependent fashion, indicating that GLP-1R mediates its effects in CSMCs through activation of adenylyl cyclase, leading in turn to cAMP-dependent activation of various second messenger pathways (Figure 6C)

His troponin and brain natriuretic peptide (BNP) levels were unremarkable

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Other kids his doctors, even called him fat, and worse