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Ozempic is approved only for Type 2 diabetes, not weight loss

The jury is out at the moment, but their potential to be differentiated from injectable peptides is clear and seems likely to drive significant research into small molecule modulators of GLP-1 for the treatment of diabetes, obesity and perhaps addictive behaviours for many years to come.

You can reduce the amount of muscle lost by keeping your protein intake up, doing regular resistance or strength training, and working with a dietitian to ensure your calorie deficit isnt too extreme

Combining GLP-1 agonists with metformin or exercise helps reduce regain

For optimal results, weight loss injections are usually combined with lifestyle changes, such as a balanced diet and regular exercise

Elecoglipron, an oral small molecule GLP-1 receptor agonist in adults with obesity or overweight (VISTA): A multicentre, phase 2, randomised, placebo-controlled clinical trial