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What is missing is any modern randomized controlled trial supporting the popular adult claims anti-aging, body-recomposition, sleep, or general GH-boosting benefits in healthy adults

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Laboratory and review evidence consolidated in two 2025 papers (Paschou IA et al, Endocrine 89(3):680-685, PMID 40498168

Pump malfunction must always be considered, including inflow/outflow obstruction and pump thrombosis

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