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Visfatin is also involved in adipose tissue fibrosis promoting ECM protein production including Collagen type VI, MMP-2 and MMP-9 [190] (Fig
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The gastrointestinal side effects, whilst common, were manageable and typically resolved with continued treatment or dose adjustment
The vagus nerve in part mediates this effect [33]

Body aches , joint pain , and muscle pain appear in a minority of patients
