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It has been used to treat conditions such as inflammatory bowel disease (IBD), ulcers, and leaky gut syndrome by promoting mucosal healing and reducing inflammation within the gut (Jain et al., 2021)

| Overall Semaglutide is a powerful GLP-1 agonist that is designed appropriate for once-weekly use

2 The two dominant incretins are glucagon-like peptide-1 (GLP-1), secreted by enteroendocrine L cells (located in the ileum and colon), and glucose-dependent insulinotropic peptide (GIP), secreted by K cells (located mainly in the duodenum)

2024, doi:10.1007/s12020-024-03998-8

Nauck MA, Petrie JR, Sesti G, et al

Safety and pharmacokinetics of bimagrumab in healthy older and obese adults with body composition changes in the older cohort