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Description
GLP-1R in its inactive apo-state is constantly moving but prefers to adopt a closed ECD conformation in absence of peptide binding (55)
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doi: 10.1038/nrg3897 141 MaesT.MascarC.RotllantD.LufinoM
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One study warns that these drugs produce unsustainable volumes of toxic waste and non-degradable solid supports ( [20] ), prompting CDMOs to pursue greener chemistries and solvent-recovery systems (for example, water-based or continuous SPPS) as part of future-capex planning ( [21] ) ( [20] )