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This is done to: oProvide additional guidance and instructions for follow-up or continuation of care as needed oContact patient or schedule additional follow-up visit if needed - All ER visits and hospitalizations are reviewed by the Medical Director and Chief Medical Officer weekly The core components of the IVIM protocol: The IVIM protocol is based on four pillars of support: 1

However, the findings of the CALERIE study suggest that CR alone could be sufficient to provide significant mood improvements

ASPREE Investigator Group

Serious side effects, such as hypoglycemia (low blood sugar), can also occur

Limit or avoid alcohol to reduce the risk of stomach upset or ulcers

In the dedicated MASLD Phase 2a trial, 86% of participants on 12 mg achieved normal liver fat levels at 24 weeks