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GLP-1RA can also affect the process of skin aging through interaction with advanced glycation end products (AGEs) and RAGE (receptors of AGEs) activation

A population-based cohort study of nearly 114,000 patients with T2D found that use of GLP-1s, compared with SGLT-2 inhibitors, was associated with a 27% higher relative risk of being diagnosed with GERD and a 55% higher relative risk of GERD-related complications

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Reducing the risk of major cardiovascular events (like heart attacks or strokes) in people with type 2 diabetes and heart disease

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