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Severe or persistent vomiting can lead to dehydration, electrolyte imbalances, and treatment discontinuation

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Giblin et al., 'Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials', Diabetes Obes

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GLP-1 powerfully slows how quickly your stomach empties food into your intestines, contributing to prolonged fullness

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95% CI 2.86, 12.94

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doi: 10.2337/dc25-S016

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The 28% nausea rate at maximum dose is notably lower than Semaglutides 44%

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