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The day of the week and time of day matter too

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Why Am I Sleeping So Poorly on a GLP-1 Medication

Sitagliptin and Metformin Coadministration In a two-day study in healthy subjects, sitagliptin alone increased active GLP-1 concentrations, whereas metformin alone increased active and total GLP-1 concentrations to similar extents

In contrast, injectable therapies often require refrigeration, temperature monitoring, injection supplies, and proper sharps disposal
