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These medications should be a jump start toward a healthy lifestyle with diet and exercise, not a substitute, says the lead author, John Gabriel Horneff III, MD, an associate professor of orthopedic surgery at the University of Pennsylvania in Philadelphia

Incorporation of a trifluoromethyl group at the 6-position of the tetrahydropyran ring in omarigliptin (with a (2R, 3S, 5R, 6S) configuration) was found not only to enhance the pharmacokinetic profile in mice but also to maintain robust DPP-4 inhibitory activity

Peroxisome Proliferator-Activated Receptor-Gamma Gene Expression in Orbital Adipose/Connective Tissues is Increased During the Active Stage of Graves' Ophthalmopathy

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