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GLP-1 receptor agonists can trigger heartburn and reflux in some patients by slowing stomach emptying and increasing intragastric pressure

Can they do the same for everyone else?

Adolescents with obesity prescribed a GLP-1 receptor agonist are less likely to have suicidal ideation or a suicide attempt than those with obesity treated with lifestyle intervention, according to new data

Our functional and structural data suggest that receptor conformational dynamics associated with flexibility of the peptide N-terminal activation domain may be a key determinant of agonist efficacy

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