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Description
Native GLP-1 is not suitable for treatment, since the peptide is degraded rapidly within minutes by the enzyme dipeptidyl-peptidase-IV (DPP-4) (31, 32)
But it shouldnt be considered a stand-alone miracle for all things obesity related
J Neuroinflammation 16(1):242 [DOI] [PMC free article] [PubMed] [Google Scholar] Sheahan KH, Wahlberg EA, Gilbert MP (2020) An overview of GLP-1 agonists and recent cardiovascular outcomes trials
We dont have robust long-term human pregnancy data yet (the medications are simply too new), and the preliminary information we do have suggests caution is warranted
Efficacy and safety of lixisenatide once-daily versus placebo in patients with type 2 diabetes mellitus insufficiently controlled on met-formin (GetGoal-F1) [Abstract] Diabetologia
fed female APOE*3-Leiden.CETP mice cholesterol-containing western-type diet for 5 weeks to induce atherosclerosis and then treated them with exendin-4 for the next 4 weeks ( in vivo
