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The WHO released its first global guideline for GLP-1 obesity treatment, recognizing obesity as a chronic disease

High-profile celebrities have publicly discussed using GLP-1 receptor agonists for weight management, sparking global interest in semaglutide and tirzepatide

Combination cagrilintide and semaglutide therapy is associated with a 15.6% weight loss and 2.2% reduction in HbA1c among adults with obesity and type 2 diabetes, according to a speaker.In findings from a phase 2a trial that were presented at the American Diabetes Association Scientific Sessions and simultaneously published in The Lancet, 71% of adults receiving coadministered

Dual- and triple action approaches which simultaneously target multiple pathways, for example, GLP1R/GIP (tirzepatide), GLP1R/GIP/glucagon (retatrutide) or amylin/GLP1R (CagriSemra) appear more potent and may push weight reduction to the mid-20% range and possibly beyond, while oral options seek to deliver levels of efficacy seen with injectables

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NESS 2022 Abstracts: A Bariatric Surgery Derived Gut Metabolite is a Potent Single and Combination Oral Therapy for Type 2 Diabetes (T2D)