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This staggered approach mirrors standard practice with semaglutide and tirzepatide, where slow titration dramatically reduces nausea, vomiting, and diarrhea

10.1016/s0140-6736(23)01200-x [DOI] [PubMed] 103.Wadden TA, Chao AM, Machineni S, et al

When blood sugar levels stabilize within a healthier range, patients with type 2 diabetes frequently experience reduced fatigue

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If you're taking a GLP-1 receptor agonist (semaglutide) or a dual GLP-1/GIP receptor agonist (tirzepatide) for weight management, the results are probably impressive

Energy and fatigue management is another commonly cited rationale