is jardiance a glp 1 agonist Jardiance® vs. Ozempic®: Similarities and Differences Jardiance vs Ozempic: Key Differences,

In a systematic review of randomized clinical trials, 6.5% of those using a GLP-1RA discontinued it due to adverse events versus 3.6% of those on placebo (16), but these rates appear to be higher in observational studies where factors associated with discontinuation were an age of 65 years or older and GI adverse events with treatment (21)

Robbins says

Instead, it contains ingredients that have been studied for potential effects on GLP-1 levels, appetite, blood sugar, and body composition

These medicines work best when used as ongoing treatment, similar to medicine for high blood pressure or diabetes

Piotrowski K, Becker M, Zugwurst J, Biller-Friedmann I, Spoettl G, Greif M, Leber AW, Becker A, Laubender RP, Lebherz C, Goeke B, Marx N, Parhofer KG, Lehrke M: Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans

The cost of semaglutide, particularly when used for weight loss (under the brand name Wegovy), tends to be on the higher end compared to other weight loss medications