tirzepatide versus semaglutide as Compared with for the Treatment of Obesity Tirzepatide vs Semaglutide – Weight
Description
While highly effective, can semaglutide cause vomiting

The people who struggle most are the ones who try to eat the same way they did before, just less of it

[DOI] [PMC free article] [PubMed] [Google Scholar] 700.Barrera J.G., Jones K.R., Herman J.P., D'Alessio D.A., Woods S.C., Seeley R.J

The treatment effects of interest, including the differences in the respective primary endpoints of interest from baseline to the defined primary timepoint, will be summarized using an analysis of covariance (ANCOVA) for the treatment regimen estimand and a mixed model for repeated measures (MMRM) for the efficacy estimand, both with treatment and strata as fixed effects and the baseline response variable as a covariate
The reduction was 5% and 33.1% in the placebo group

While theres no set timeline on restarting GLP-1 RAs, currently these medications arent recommended if youre breastfeeding
