retatrutide triple agonist glp-1 gip glucagon phase 2 nejm 2023 Retatrutide, a (GLP1, GIP, glucagon), just released trial results demonstrating 25% weight loss in half of people with #obesity. This amount of weight loss has not been accomplished Retatrutide is a triple-agonist drug
Description
Aim for clear or pale-yellow urine as your hydration indicator
Weight loss may plateau over time due to counterregulatory hormonal mechanisms that resist further reductions

Zaccardi F, Htike ZZ, Webb DR, Khunti K, Davies MJ
I.JavaidS.HameedA.et al (2024)

Effects of semaglutide on stroke subtypes in type 2 diabetes: post hoc analysis of the randomized SUSTAIN 6 and PIONEER 6
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GLP-1 slows gastric emptying
