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doi:10.1186/s12902-017-0228-9 176

These are related to changes in blood sugar levels and the bodys response to the absence of semaglutide

Dehydration from High Blood Sugar: If blood sugar is too high for a long time, the body loses fluids, which can lead to an electrolyte imbalance and palpitations

Use an electrolyte supplement or add sea salt to meals and water if needed

Typically, people start on a lower dose of semaglutide and build up to receiving a 2.4 mg dose of semaglutide

This guide covers: What the STEP clinical trials actually found Success rates at key weight loss thresholds (5%, 10%, 15%, 20%) The timeline from first injection through full results How results differ from Ozempic (same medication, different context) Factors that predict better or worse outcomes Health improvements beyond scale weight What happens when treatment stops Setting realistic expectations for your situation Key Takeaways Clinical trials show 14.9% average weight loss over 68 weeks (approximately 16 months) with Wegovy 86% of patients lose at least 5% of body weight, the threshold for clinical significance About one-third achieve 20% or greater loss , representing the dramatic transformations often highlighted Roughly 14% dont achieve meaningful results despite taking the medication as directed Timeline is gradual , with most significant progress occurring between months 4-9 at maintenance doses The dose escalation takes 16-20 weeks , meaning full effectiveness isnt reached until month 4-5 Results match Ozempic since both contain semaglutide, though Wegovys maximum dose is slightly higher (2.4mg vs