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Analogous to the pancreatic islet, adipocytes adapt during pregnancy and lactation, when PRL values may exceed 200 g/L, including neural (dopaminergic) changes that increase appetite, food intake, and redistribute nutrients, lipid storage from abdominal tissues to mammary glands (54)

doi:10.1016/j.cyto.2013.04.016 154

*Correspondence: Parisa Alsadat Dadkhah, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Spreading of Toxin Effects In very rare cases, the effects of Botox can spread to other parts of the body, resulting in symptoms including weakened muscles, trouble swallowing, or breathing problems