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Combining semaglutide with topiramate may produce additive weight loss effects due to their different mechanisms, though clinical evidence specifically comparing dual therapy is limited

Let's take, you know, critics from different groups or philosophies, whether it's starting strength or other, and just think of the what you're trying to do

[DOI] [PMC free article] [PubMed] [Google Scholar] 94.Li Y, et al

Because it produces greater weight loss roughly 20% in REDEFINE 1 versus about 15% for semaglutide and steatohepatitis resolution is closely tied to the magnitude of weight loss
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Most individuals experience a 15% decrease in their overall body weight Semaglutide What are the benefits
