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doi: 10.1038/nrdp.2017.81 95 EnriquezJ

If you are vomiting after your injection, especially if it happens repeatedly, contact your provider immediately

insulin glargine The SURPASS-AP-Combo trial enrolled 917 adults with type 2 diabetes (age 18 years, inadequately controlled by previous metformin therapy and insulin-naive), who received tirzepatide 5 mg (n = 230), 10 mg (n = 228), 15 mg (n = 229), or insulin glargine (n = 230)

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doi: 10.1111/dom.14551

However, some healthcare providers may consider prescribing both medications together off-label in select patients who have not achieved adequate weight loss with monotherapy