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[33] Studies suggest that tirzepatide can lower the risk of cardiovascular disease and improve cardiovascular outcomes: GIP and GLP-1 are natural incretin hormones that play a role in liver function

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Trial SURPASS-1 (Lancet 2021) Population 478 adults with T2D, monotherapy vs placebo

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conducted a pre-specified cardiovascular meta-analysis that included all seven randomized controlled trials with a duration of at least 26 weeks from the SURPASS trials [61]