semaglutide period changes and metformin improve menstrual cyclicity in overweight/obese women with polycystic ovary syndrome: a randomized trial Do GLP-1 weight loss drugs
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10.1111/1753-0407.70063 64 YaoH.ZhangA.LiD.WuY.WangC.-Z.WanJ.-Y.et al (2024)

However, retatrutide is still investigational, tirzepatide has longer real-world experience, and side effects may be slightly more pronounced with retatrutide due to the triple-agonist mechanism

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Acute Kidney Injury Due to Volume Depletion: Monitor renal function in patients reporting adverse reactions that could lead to volume depletion

Prescribing decisions must be made by qualified healthcare professionals following comprehensive assessment, including evaluation of cardiovascular risk factors, renal function, and potential drug interactions
