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[DOI] [PubMed] [Google Scholar] 8.Liu D, Archer N, Duesing K, Hannan G, Keast R

Estradiol indirectly increases POMC activity through its effects on NPY/AgRP neurons (82, 83)

The non-peptide nature provides resistance to enzymatic degradation, including lack of susceptibility to DPP-4, and promotes favourable bioavailability

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Maintaining a consistent weekly schedule helps support steady hormone signaling and predictable progress