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With continued semaglutide, mean body weight change from week 20 to week 68 was 7.9% vs +6.9% with the switch to placebo (difference, 14.8 [95% CI, 16.0 to 13.5] percentage points

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These include severe or persistent abdominal pain that may radiate to the back (possible pancreatitis), signs of gallbladder problems such as upper right abdominal pain, fever, or jaundice, sudden changes in vision (possible worsening diabetic retinopathy), severe vomiting or diarrhea leading to dehydration, and any symptoms of a severe allergic reaction

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