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Narrative synthesis was conducted due to heterogeneity in study designs and outcome definitions

Long-term users report sustained benefits, including better habit formation and metabolic resilience

Recent Findings Since semaglutide may cause delayed gastric emptying and residual gastric contents, controversies arise on preoperative medication management, adequate preoperative fasting periods, utilization of gastric ultrasound, and rapid sequence induction and intubation to mitigate the risks of regurgitation and pulmonary aspiration of gastric contents during anesthesia care

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Food and Drug Administration has accelerated approval for Wegovy (semaglutide) to treat metabolic dysfunction-associated steatohepatitis (MASH)a progressive liver disease marked by inflammation and scarringin adults with moderate to advanced fibrosis
