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Conclusion GLP-1 RAs may significantly lower the combined risk of mortality and hospitalization in patients with HFpEF

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Triple agonist retatrutide yielded 28.7% weight loss at 68 weeks, besting Zepbounds Phase III data, while also showing benefit in knee osteoarthritis pain.

Eligibility criteria for selecting studies Eligible randomised controlled trials enrolled adults with type 2 diabetes who received GLP-1RA treatments and compared effects with placebo or any GLP-1RA drug, with a follow-up duration of at least 12 weeks

Zur Behandlung von Risikopatienten mit Diabetes mellitus Typ 2 stehen verschiedenen Diabetesmedikamente zur Verfgung