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Editor: Eliza Barclay Graphics: Javier Zarracina Copy editor: Tanya Pai Project manager: Susannah Locke Special thanks: Mohsin Ali for research assistance and Hilda Bastian for advice on searching the medical literature

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a - b , Insulin secretion in islets isolated from wild-type (WT, grey bars) and Glp-1r knockout (KO, white bars) mice at high or low glucose

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