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While NAION is rare, it has no cure and can cause permanent vision loss

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doi:10.1016/j.jacc.2021.12.012 Invokana (canagliflozin) [package insert]

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Armstrong MJ, Houlihan DD, Rowe IA, Clausen WH, Elbrond B, Gough SC, Tomlinson JW, Newsome PN