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Weight loss during this period is typically modest, primarily due to reduced caloric intake

The pancreas typically produces adequate digestive enzymes in patients without pancreatic insufficiency, and GLP-1 receptor agonists do not directly inhibit enzyme synthesis

These interactions can modulate immune responses, reduce inflammatory signaling, strengthen tight junctions between intestinal cells (reducing permeability), and potentially support the environment in which L-cells function optimally

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Additional investigations should focus on populations with optimal cardiovascular health in order to clarify the efficacy of GLP-1 RAs in primary prevention

doi: 10.3390/molecules27051713