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[7] [8] A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings

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Cappellani D, Macchia E, Falorni A, Marchetti P

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By targeting both metabolic and neurodegenerative pathways, GLP-1 receptor agonists represent a multifaceted approach to PD treatment, offering hope for better disease management and improved patient outcomes

To explore the effect of ghrelin and GLP-1 on the cellular excitability of Glp1r + Ghsr + neurons, we studied these neurons intracellular signalling mechanisms
