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Experimental approaches Several pharmacologic treatments are presently being evaluated in phase 1 or 2 clinical trials
These drugs were originally developed to treat Type 2 diabetes, but they have gained popularity for their significant weight loss effects, helping people lose 15% to 20% of their body weight in clinical trials
Today, it seems that the most relevant approach is a three-step strategy: Support GLP-1 users by: Rebranding or launching products to overcome aftereffects with enhanced protein content, collagen or prebiotics
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Most anesthesiologists now ask patients to hold GLP-1s for 1 week (daily drugs) or 2 weeks (weekly injections) before elective surgery
At supplemental doses of 3 to 5 grams per day, which is the range studied for sleep and metabolic benefits, glycine is generally recognized as safe
