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These typically lessen with continued use and dosage adjustments

Their germline phenotypes were analyzed by staining dissected gonads with EdU-labeling kit and anti-HIM-3 (a marker for meiotic cells) antibody at adult stage (4 days past L1)

GLP-1RAs can modulate intracellular calcium homeostasis to prevent reperfusion injury directly in cardiomyocytes [164]

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Additionally, agents capable of positively modulating more than one peptide hormone receptor simultaneously, such as tirzepatide or the recently characterised GL-0001 peptide, could offer an even more exciting avenue to help realise the potential of gut-derived hormones to treat bone disease

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