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GLP-1 medications like Ozempic, Wegovy, and Mounjaro have revolutionized diabetes management and weight loss for millions of Americans

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Summary Obesity is a chronic progressive disease with increasing prevalence in the United States and around the world

Conclusion In this NMA, tirzepatide 10 and 15 mg were associated with improved efficacy versus liraglutide, improved or comparable efficacy versus semaglutide, and all interventions had a generally comparable safety profile for achieving weight reduction and reducing cardiometabolic risk factors among patients with obesity or overweight.

The beneficial effect of TZT in T2DM and obesity is related to direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of body weight

Researchers warn that anyone taking Wegovy, Ozempic, Saxenda or Victoza may be at a higher risk of several digestive issues.