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When that person spends months on a supplement instead of having a conversation with their doctor, thats time and opportunity lost
While dopamine efflux is preserved in ex vivo slices treated with amphetamine [157], phasic dopamine release is only observed in in vivo studies with preserved VTA inputs to the accumbens [158]
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No randomized controlled trial has tested sublingual tirzepatide for weight loss, blood sugar control, or any other outcome
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The takeaway: Bakri is right that retatrutide is the most effective drug in the class, but "way less side effects" overstates the safety profile
