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Description
Contrary to GLP-1R mono-agonist, whose efficacy is limited by dose-dependent gastrointestinal events, the new triple agonists can simultaneously increase energy expenditure, reduce food intake, and improve glucose control by engaging all three receptors at once

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SLE: Systemic lupus erythematosus

Additionally, physicians who lack experience or are uncomfortable prescribing SUD treatments will already have extensive experience prescribing GLP-1s

without a substantial pharmacokinetic relationship since the two classes function through different mechanisms
