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Nature 467:11141117

10.1152/ajpcell.00194.2015 22 DunlayS
While the causal role of inflammation in T2DM is uncertain, circulating pro-inflammatory proteins (e.g., IL-1, IL-6, IL-18, CRP, TNF-) are linked to T2DM risk [203]

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Dulaglutide and cardiovascular outcomes in T2D (REWIND): A double-blind, randomised placebo-controlled trial
Overall exposure (AUC) to pramlintide is relatively constant with repeat dosing of SYMLIN, indicating no bioaccumulation
