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In contrast, the glucose-lowering effect of T3 treatment could not be observed in the hypothyroid mice four hours after injection of a single dose of T3 (MMI + T3-4h mice), although these mice displayed very high levels of circulating T3 (Supplementary Fig
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8-12 It should also not be forgotten that oral semaglutide is now an option for patients who are not good candidates for injectable glucose-lowering therapy
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