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In AD models, CBD can lead to tau degradation though activation of autophagy pathways that may assist in the early stages of AD treatment [22]

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Taken together, these pleiotropic effects, ranging from anti-inflammatory, neurotrophic actions to dopaminergic and gut-mediated modulation and appetite-regulating effects, support a multimodal model of GLP-1 RA activity relevant to psychiatric disorders [26,83]

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Combined with reduced appetite making it harder to consume adequate fluids, dehydration is a real and common risk

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