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Studies consistently show 10 to 30 percent of metformin users develop low b12 levels over years of use

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Everyones likelihood of risks and benefits is highly individualized, but these medications can touch on very personal issues, like weight status, weight stigma, body image, chronic illness management, and future disease risk, which must be carefully considered and handled with compassion plus a focus on currently available scientific evidence

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To maintain that firmness long-term, periodic maintenance treatments are often recommended