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Conclusion: This review synthesizes current evidence on the safety and effectiveness of GLP-1RAs in weight management and potential cardiovascular protection

The GLP-Squared Oral Protocol from PlexusDx is a compounded dual-compound GLP-1 formulation combining Semaglutide and Tirzepatide as a daily oral tablet, prescribed by licensed providers as a clinical step-up

Their lead candidate, ECC5004, is an oral GLP-1 agonist licensed to AstraZeneca for global development (excluding China), while Eccogene retains co-development and co-commercialization rights in China