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The reason for acute onset of nAMD in this patient is unknown
Originally for Diabetes: First approved in 2017 for type 2 diabetes, its powerful weight loss effects led to expanded use for obesity treatment

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Scientists reported that zuclomiphene may have potential deleterious effects on the male reproductive system. This is because it inhibits the signals in your body that result in normal testosterone production

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Switching requires new titration (812 weeks), may temporarily restart GI side effects, and will need insurance reauthorization but the mechanism shift from dual to triple agonism may produce meaningful additional weight loss
