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Clinical data shows that approximately half of weight loss reverses within 12 months after discontinuation, making long-term medication continuity essential for sustained results

The balance between oxidative demand and redox buffering capacityas well as between catabolic drive and anabolic substrate supportmay therefore become an important determinant of tissue resilience and the durability of pharmacologically induced weight loss

Some patients respond excellently to medication alone, while others achieve superior, lasting results through surgical intervention combined with medication and lifestyle changes

Understanding your body's individual response pattern is the key to unlocking sustained progress

The TRIUMPH-1 trial enrolled adults with a BMI of 30 or above, or a BMI of at least 27 plus a weight-related health condition