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Moreover, the acidification of the tumor microenvironment due to the secretion of lactate, the final glycolytic product, contributes to cancer cell invasiveness and immune suppression

NICE guideline NG28 recommends regular monitoring of HbA1c levels (typically every 36 months until stable, then 6-monthly) and assessment of treatment response, tolerability, and cardiovascular risk factors for patients taking GLP-1 receptor agonists
"Pretty much everybody has a good intention to eat healthily today, but somehow that gets eroded when you walk down the high street and there are coffee shops and cafes and muffins

Some patients find that nausea and other side effects diminish with time and dietary adjustments

Before January 2026, the maximum weekly dose was 2.4mg