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Description
Circulation 2011;123(10):1098-107

Key Takeaways Tirzepatide activates two incretin hormone pathways (GLP-1 and GIP)

Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial
Pausing or stopping the medication is rarely necessary, and is typically only considered if the shedding is severe or persistent

The AAD also notes lasers as a safe, painless option that requires ongoing sessions to maintain gains

Fecal microbiota transplantation improves intestinal inflammation in mice with ulcerative colitis by modulating intestinal flora composition and down-regulating NF-kB signaling pathway
