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GLP-1 Reduz apetite e aumenta saciedade GIP Melhora metabolismo da glicose Glucagon Acelera queima de gordura -28,3% Reduo mdia de peso corporal TRIUMPH-1 Fase 3 80 semanas n=2.339 Extenso 104 sem (BMI35): at -30,3% TRIPLO AGONISTA ATIVAO SIMULTNEA 45,3% dos pacientes atingiram 30% de perda vs