glp-1 treatment for newly diagnosed diabetes guidelines Receptor Agonists the Management of Type 2 Diabetes: Pharmacist Focus on the Evolving Landscape GLP-1 receptor agonists are transforming

Clinical implementation of incretin-based therapies for the management of T2DM, which diminish postprandial glycaemia, in part by slowing gastric emptying, is widespread

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Because of the slowed gastric emptying, many patients have gastrointestinal side effects that can often limit a patients ability to take these drugsespecially at the high doses recommended for weight loss

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10.1038/s41366-020-0618-3 [Google Scholar] Christoffersen B, Sanchez-Delgado G, John LM, Ryan DH, Raun K, Ravussin E (2022) Beyond appetite regulation: targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss

This exclusion is significant considering that patients with obesity have a higher risk of developing depression 24