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CVS Caremark is a pharmacy benefit manager (PBM), not an insurer

Weight loss caused by taking Orlistat may improve blood sugar control for diabetics, while also modestly reducing the onset of type 2 diabetes and blood pressure, both at similar levels caused by positive changes in lifestyle and diet

UK sites participating in global Phase 3 trials

445 participants: 12 mg: average 28.7% body weight loss WOMAC knee pain scores dropped by up to 75.8% More than 1 in 8 patients became completely pain-free Systolic blood pressure improved by 14.0 mmHg TRANSCEND-T2D-1 Type 2 diabetes (40 weeks) Published March 2026

Mounjaro's manufacturer, Lilly, also lists similar side effects including decreased appetite and indigestion and management tips

Retrieved March 10, 2026, from
